4-octyl Itaconate from CAYMAN CHEMICAL COMPANY
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| Product Name | 4-octyl Itaconate |
| Description | A prodrug form of itaconate; hydrolyzed to itaconate by esterases in C2C12 cells and LPS-activated mouse macrophages; increases Nrf2 protein levels and expression of Nrf2 target genes and enhances LPS-induced Nrf2 stabilization in mouse macrophages; decreases serum levels of IL-1β and TNF-α, increases Nrf2 protein expression, and protects against LPS-induced lethality in wild-type, but not Nrf2 knockout, mice at 50 mg/kg, |
| Size | 100 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | Octylitaconate IRG-1 lipopolysaccharide Nrf-2 IL1β TNFα antiinflammatory WT Succinic methylenesuccinate β-Monooctylitaconate KEAP1 KEAP-1 |
| Gene, Accession, CAS # | CAS: 3133-16-2 |
| Catalog # | 25374-100 |
| Price | $141.00 |
| Order / More Info | 4-octyl Itaconate from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY