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Product Name | SR 2211 |
Description | Selectively binds RORγ (Ki = 105 nM), acting as an inverse agonist of constitutive in vitro RORγ activity (IC50 = 320 nM); significantly inhibits gene expression of IL-17 and IL-23 receptor in activated EL-4 mouse T lymphocytes when given at 5 µM |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | receptors RORgamma RORγ inflammation autoimmune diseases multiple sclerosis rheumatoid arthritis IL-17 TH17 cells lymphocytes inverse agonists mouse murine SR-2211 SR2211 RORg ROR-γ ROR.gamma. ROR-.gamma. ROR-g IL17 IL23 ILs 17 23 EL4 EL-4 EL 4 |
Gene, Accession, CAS # | CAS: 1359164-11-6 |
Catalog # | 11972-5 |
Price | $134.00 |
Order / More Info | SR 2211 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |