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Product Name | MRS1754 |
Description | An adenosine A2B receptor antagonist (Ki = 1.97 nM); selective for adenosine A2B receptors over adenosine A1, A2A, and A3 receptors (Kis = 403, 503, and 570 nM, respectively); increases 28-day survival, as well as decreases peritoneal bacterial growth and plasma levels of IL-6, TNF-α, and MIP-2, in a mouse model of CLP-induced sepsis from 0.5-10 mg/kg; reduces disease severity in a mouse model of EAE at 1 mg/kg |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | MRS-1754 IL6 TNFα MIP2 |
Gene, Accession, CAS # | CAS: 264622-58-4 |
Catalog # | 33501-10 |
Price | $185.00 |
Order / More Info | MRS1754 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |