ODM-201 from CAYMAN CHEMICAL COMPANY
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| Product Name | ODM-201 |
| Description | An androgen receptor antagonist (Ki = 11 nM); inhibits AR transactivation in U2OS osteosarcoma cells expressing human wild-type and mutant ARs (IC50s = 65, 66, 1,500, and 1,782 nM for wild-type, ARF876L, ARW741L, and ART877A, respectively); prevents androgen-induced AR nuclear translocation in AR-overexpressing HS-HEK293 and LNCaP cells; suppresses androgen-induced proliferation of VCaP cells (IC50 = 230 nM); reduces tumor growth in a VCaP castrated mouse xenograft model at 50 mg/kg per day; inhibits tumor growth without increasing serum testosterone levels in a VCaP intact mouse xenograft model , |
| Size | 1 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | BAY 1841788 |
| Gene, Accession, CAS # | CAS: 1297538-32-9 |
| Catalog # | 25643-1 |
| Price | $44.00 |
| Order / More Info | ODM-201 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY