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Product Name | β-Secretase Inhibitor IV |
Description | An inhibitor of BACE1 and 2 (IC50s = 15 and 230 nM for human BACE1 and 2, respectively); has >500-fold selectivity for BACE1 and 2 over the aspartyl proteases renin and cathepsin D; inhibits secretion of APP (IC50 = 29 nM) in HEK293T cells transfected with a truncated human APP; inhibits formation of the Aβ peptides Aβ38, Aβ40, and Aβ42 in primary chick neurons (IC50s = 3.7, 4.7, and 4.8 nM, respectively) |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | Axon 1125 Axon1125 38 40 42 BACE 1 BACE2 |
Gene, Accession, CAS # | CAS: 797035-11-1 |
Catalog # | 23388-1 |
Price | $253.00 |
Order / More Info | β-Secretase Inhibitor IV from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |