C18 from CAYMAN CHEMICAL COMPANY
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| Product Name | C18 |
| Description | A covalent GPX4 inhibitor (IC50 = 120 nM); inhibits the growth of MDA-MB-468, BT-549, and MDA-MB-231 cells (IC50s = 10, 75, and 12 nM, respectively); increases lipid peroxidation and oxidized MDA levels in MDA-MB-231 cells at 10 and 20 µM; decreases mitochondrial volume and induces mitochondrial crest and outer membrane degradation in MDA-MB-231 cells at 20 µM; reduces tumor volume and weight, without affecting body weight, in an MDA-MB-231 mouse xenograft model at 5, 10, or 20 mg/kg per day |
| Size | 5 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | C-18 GPX-4 MDAMB-468 231 MDA-MB468 MB231 MDAMB468 MDAMB231 BT549 |
| Gene, Accession, CAS # | CAS: 2922824-09-5 |
| Catalog # | 39432-5 |
| Price | $96.00 |
| Order / More Info | C18 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY