EED226 from CAYMAN CHEMICAL COMPANY

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Product NameEED226
DescriptionA potent and allosteric inhibitor of PRC2 (IC50 = 23.4 nM in an enzyme assay with H3K27me0 peptide as the substrate); exhibits dose-dependent displacement of H3K27me3 binding to the EED subunit of PRC2; decreases global H3K27me3 and H3K27me2 in G401 cells and H3K27me3 in Karpas422 lymphoma cells in a dose-dependent manner; reduces proliferation of Karpas422 lymphoma cells in vitro and slows growth of Karpass422 xenografts in vivo
Size1 mg
Concentrationn/a
Applicationsn/a
Other NamesEED 226 PRC
Gene, Accession, CAS #CAS: 2083627-02-3
Catalog #22031-1
Price$37.00
Order / More InfoEED226 from CAYMAN CHEMICAL COMPANY
Product Specific Referencesn/a
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640

Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
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