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Product Name | EED226 |
Description | A potent and allosteric inhibitor of PRC2 (IC50 = 23.4 nM in an enzyme assay with H3K27me0 peptide as the substrate); exhibits dose-dependent displacement of H3K27me3 binding to the EED subunit of PRC2; decreases global H3K27me3 and H3K27me2 in G401 cells and H3K27me3 in Karpas422 lymphoma cells in a dose-dependent manner; reduces proliferation of Karpas422 lymphoma cells in vitro and slows growth of Karpass422 xenografts in vivo |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | EED 226 PRC |
Gene, Accession, CAS # | CAS: 2083627-02-3 |
Catalog # | 22031-1 |
Price | $37.00 |
Order / More Info | EED226 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |