AF 12198 from TOCRIS BIOSCIENCE

TOCRIS BIOSCIENCE

TOCRIS BIOSCIENCE

Tocris House, IO Centre

Moorend Farm Avenue

Avonmouth, Bristol, BS11 0QL UNITED KINGDOM

Phone: + 44 (0)117 916 3333

Fax: + 44 (0)117 916 3344

Email: customerservice@tocris.co.uk

Website: http://www.tocris.com

U.S.A. OFFICE: Tocris Bioscience
16144 Westwoods Business Park
Ellisville, Missouri 63021 USA

Telephone: (800) 421-3701/(636) 207-7651
Fax: (800) 483-1993/(636) 207-7683
E-mail: customerservice@tocrisusa.com

AF 12198 from TOCRIS BIOSCIENCE

Name	AF 12198
Description	Minimum Purity: > 98%. Potent and selective antagonist for the human type I interleukin-1 (IL-1) receptor (IC50 values are 8 nM, > 6.7 mM and > 200 mM for human type I, human type II and murine type I IL-1 receptors respectively). Blocks IL-1-induced expression of ICAM-1 and E-selectin in HUVECs and IL-1beta induction of IL-8 in human dermal fibroblasts. Reduces IL-1beta-induced IL-6 production and exhibits anti-inflammatory activity in vivo.
Size	1mg
Applications	n/a
Catalog #	1793
Price	€259
Other Names	CAS No. [185413-30-3]
Supplier Data Page	AF 12198 from TOCRIS BIOSCIENCE

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