AP 24534 from TOCRIS BIOSCIENCE

TOCRIS BIOSCIENCE

TOCRIS BIOSCIENCE

Tocris House, IO Centre

Moorend Farm Avenue

Avonmouth, Bristol, BS11 0QL UNITED KINGDOM

Phone: + 44 (0)117 916 3333

Fax: + 44 (0)117 916 3344

Email: customerservice@tocris.co.uk

Website: http://www.tocris.com

U.S.A. OFFICE: Tocris Bioscience
16144 Westwoods Business Park
Ellisville, Missouri 63021 USA

Telephone: (800) 421-3701/(636) 207-7651
Fax: (800) 483-1993/(636) 207-7683
E-mail: customerservice@tocrisusa.com

AP 24534 from TOCRIS BIOSCIENCE

Name	AP 24534
Description	Minimum Purity: > 98%. Potent multi-kinase and pan-BCR-ABL inhibitor. Displays potent activity against cell lines expressing native BCR-ABL or BCR-ABLT3151 (IC50 values are 0.37 and 2.0 nM respectively); also inhibits other ABL kinase domain mutants at nanomolar potencies. Exhibits inhibitory activity against PDGFRalpha, c-Src and c-Kit (IC50 values are 1.1, 5.4 and 12.5 nM respectively); potently inhibits FGFR and VEGFR family kinases. Orally active.
Size	50mg
Applications	n/a
Catalog #	4274
Price	€875
Other Names	Ponatinib \| CAS No. [943319-70-8]
Supplier Data Page	AP 24534 from TOCRIS BIOSCIENCE

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