API-2 from TOCRIS BIOSCIENCE

TOCRIS BIOSCIENCE

TOCRIS BIOSCIENCE

Tocris House, IO Centre

Moorend Farm Avenue

Avonmouth, Bristol, BS11 0QL UNITED KINGDOM

Phone: + 44 (0)117 916 3333

Fax: + 44 (0)117 916 3344

Email: customerservice@tocris.co.uk

Website: http://www.tocris.com

U.S.A. OFFICE: Tocris Bioscience
16144 Westwoods Business Park
Ellisville, Missouri 63021 USA

Telephone: (800) 421-3701/(636) 207-7651
Fax: (800) 483-1993/(636) 207-7683
E-mail: customerservice@tocrisusa.com

API-2 from TOCRIS BIOSCIENCE

Name	API-2
Description	Selective inhibitor of Akt (protein kinase B) signaling; displays minimal inhibition of PKC, PKA, SGK and p38 pathways. Inhibits phosphorylation and activation of downstream targets of Akt including Bad, GSK-3beta and AFX. Induces apoptosis and growth arrest in vitro, preferentially in human cancer cells with elevated levels of Akt. Potently and selectively inhibits growth of Akt-overexpressing tumors in mice. Inhibits DNA synthesis and displays antiviral activity against HIV-1 and -2. Purity > 99%
Size	10 mg
Applications	n/a
Catalog #	2151
Price	€225
Other Names	Triciribine \| NSC 154020 \| TCN \| CAS No: [35943-35-2]
Supplier Data Page	API-2 from TOCRIS BIOSCIENCE

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