Astemizole from TOCRIS BIOSCIENCE

TOCRIS BIOSCIENCE

TOCRIS BIOSCIENCE

Tocris House, IO Centre

Moorend Farm Avenue

Avonmouth, Bristol, BS11 0QL UNITED KINGDOM

Phone: + 44 (0)117 916 3333

Fax: + 44 (0)117 916 3344

Email: customerservice@tocris.co.uk

Website: http://www.tocris.com

U.S.A. OFFICE: Tocris Bioscience
16144 Westwoods Business Park
Ellisville, Missouri 63021 USA

Telephone: (800) 421-3701/(636) 207-7651
Fax: (800) 483-1993/(636) 207-7683
E-mail: customerservice@tocrisusa.com

Astemizole from TOCRIS BIOSCIENCE

Name	Astemizole
Description	Minimum Purity: > 99%. Orally active, potent histamine H1 antagonist (IC50 = 4 nM) that displays 20-fold, > 250-fold and > 250-fold selectivity over 5-HT, dopamine and muscarinic acetylcholine receptors respectively. Exhibits antimalarial activity in multidrug resistant strains in vitro (IC50 = 227 - 734 nM). Also potent hERG K+ channel blocker (IC50 = 0.9 nM) that displays cardiotoxicity in vivo.
Size	50mg
Applications	n/a
Catalog #	3489
Price	€49
Other Names	Hismanal \| CAS No. [68844-77-9]
Supplier Data Page	Astemizole from TOCRIS BIOSCIENCE

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