AT 101 from TOCRIS BIOSCIENCE
| Name |
AT 101 |
| Description |
Minimum Purity: > 98%. R-(-)-enantiomer of gossypol (Cat. No. 1964). Mimics the BH3 domains of Bcl-2, Bcl-XL and Mcl-1. Disrupts heterodimerization of Bcl-2 with proapoptotic family members. Induces apoptosis in vitro through activation of caspase-9; cytotoxic to multiple myeloma and drug-resistant cell lines. Delays onset of androgen-independent growth of VCaP prostate cancer xenografts in vivo. |
| Size |
10mg |
| Applications |
n/a |
| Catalog # |
3367 |
| Price |
€135 |
| Other Names |
CAS No. [90141-22-3] |
| Supplier Data Page |
AT 101 from TOCRIS BIOSCIENCE |
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