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Antigenic Specificity | PABPN1 |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | IgG |
Format | affinity purified |
Size | 20 µl, 50 µl, 100 µl, 200 µl |
Concentration | > 0.5 mg/ml |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PABPN1 Antibody is a Rabbit Monoclonal antibody against PABPN1. This gene encodes an abundant nuclear protein that binds with high affinity to nascent poly(A) tails. The protein is required for progressive and efficient polymerization of poly(A) tails at the 3? ends of eukaryotic transcripts and controls the size of the poly(A) tail to about 250 nt. At steady-state, this protein is localized in the nucleus whereas a different poly(A) binding protein is localized in the cytoplasm. This gene contains a GCG trinucleotide repeat at the 5? end of the coding region, and expansion of this repeat from the normal 6 copies to 8-13 copies leads to autosomal dominant oculopharyngeal muscular dystrophy (OPMD) disease. Related pseudogenes have been identified on chromosomes 19 and X. Read-through transcription also exists between this gene and the neighboring upstream BCL2-like 2 (BCL2L2) gene. |
Immunogen | A synthetic peptide of human PABPN1. |
Other Names | OPMD, PAB2, PABII, PABP2, PABP-2, PABPN1, Polyadenylate-binding protein 2, Nuclear poly (A) binding protein 1, Poly (A) binding protein II, Polyadenylate-binding nuclear protein 1, Poly (A)-binding protein 2, Poly (A) binding protein 2, Poly (A)-binding protein II, OPMD, OPMD, OPMD, OPMD, PAB2, PAB2, PAB2, PAB2, PABII, PABII, PABII, PABII, PABP2, PABP2, PABP2, PABP2, PABP-2, PABP-2, PABP-2, PABP-2, PABPN1, PABPN1, PABPN1, PABPN1, Polyadenylate-binding protein 2, Polyadenylate-binding protein 2, Polyadenylate-binding protein 2, Polyadenylate-binding protein 2, Nuclear poly (A) binding protein 1, Nuclear poly (A) binding protein 1, Nuclear poly (A) binding protein 1, Nuclear poly (A) binding protein 1, Poly (A) binding protein II, Poly (A) binding protein II, Poly (A) binding protein II, Poly (A) binding protein II, Polyadenylate-binding nuclear protein 1, Polyadenylate-binding nuclear protein 1, Polyadenylate-binding nuclear protein 1, Polyadenylate-binding nuclear protein 1, Poly (A)-binding protein 2, Poly (A)-binding protein 2, Poly (A)-binding protein 2, Poly (A)-binding protein 2, Poly (A) binding protein 2, Poly (A) binding protein 2, Poly (A) binding protein 2, Poly (A) binding protein 2, Poly (A)-binding protein II, Poly (A)-binding protein II, Poly (A)-binding protein II, Poly (A)-binding protein II |
Gene, Accession # | PABPN1, Gene ID: 8106, UniProt: Q86U42 |
Catalog # | abx004649 |
Price | please inquire |
Order / More Info | PABPN1 Antibody from ABBEXA LTD |
Product Specific References | n/a |
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