CHK1 Antibody from ABBEXA LTD

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Antigenic SpecificityCHK1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatpeptide affinity purified
Size80 µl, 400 µl
Concentrationn/a
ApplicationsELISA, WB
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DescriptionHRD1 is a ubiquitin ligase whose expression is induced by the unfolded protein response (UPR) following endoplasmic reticulum stress. Expression of HRD1 protects cells from apoptosis by inducing degradation of abnormally processed proteins that accumulate in the endoplasmic reticulum. HRD1 is expressed in many tissues, strongly expressed in brain, pancreas, liver, kidney and skeletal muscle. Amano T, et al. reported that Synoviolin/Hrd1 (expressed in rheumatoid synovium) is a novel causative factor for arthropathy by triggering synovial cell outgrowth through its antiapoptotic effects. HRD1 contains one ring-type zinc finger.
ImmunogenKLH-conjugated synthetic peptide between 258-287 amino acids from human CHK1.
Other NamesCheckpoint, S. pombe, homolog of, 1, CHEK1, CHK1, CHK1 checkpoint homolog (S. pombe), Serine/threonine-protein kinase Chk1, kinase Chk1, CHK1 checkpoint homolog, Cell cycle checkpoint kinase, Checkpoint kinase-1, Checkpoint, Checkpoint, Checkpoint, Checkpoint, S. pombe, S. pombe, S. pombe, S. pombe, homolog of, homolog of, homolog of, homolog of, 1, 1, 1, 1, CHEK1, CHEK1, CHEK1, CHEK1, CHK1, CHK1, CHK1, CHK1, CHK1 checkpoint homolog (S. pombe), CHK1 checkpoint homolog (S. pombe), CHK1 checkpoint homolog (S. pombe), CHK1 checkpoint homolog (S. pombe), Serine/threonine-protein kinase Chk1, Serine/threonine-protein kinase Chk1, Serine/threonine-protein kinase Chk1, Serine/threonine-protein kinase Chk1, kinase Chk1, kinase Chk1, kinase Chk1, kinase Chk1, CHK1 checkpoint homolog, CHK1 checkpoint homolog, CHK1 checkpoint homolog, CHK1 checkpoint homolog, Cell cycle checkpoint kinase, Cell cycle checkpoint kinase, Cell cycle checkpoint kinase, Cell cycle checkpoint kinase, Checkpoint kinase-1, Checkpoint kinase-1, Checkpoint kinase-1, Checkpoint kinase-1
Gene, Accession #NCBI Accession: NP_001107593.1, NP_001107594.1, NP_001231775.1, NP_001265.2, UniProt: O14757
Catalog #abx031571
Priceplease inquire
Order / More InfoCHK1 Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
181 Cambridge Science Park
Cambridge, CB4 0GJ UK
P: +44 (0) 1223 755950

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