Mothers Against Decapentaplegic Homolog 2 Phospho-Thr220 (SMAD2 pT220) Antibody from ABBEXA LTD

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Antigenic SpecificityMothers Against Decapentaplegic Homolog 2 Phospho-Thr220 (SMAD2 pT220)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formataffinity purified
Size50 µl, 100 µl, 200 µl
Concentration1 mg/ml
ApplicationsWB
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DescriptionSMAD2 (pT220) Antibody is a Rabbit Polyclonal antibody against SMAD2 (pT220). The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene ?mothers against decapentaplegic? (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signal of the transforming growth factor (TGF)-beta, and thus regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation. This protein is recruited to the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation (SARA) protein. In response to TGF-beta signal, this protein is phosphorylated by the TGF-beta receptors. The phosphorylation induces the dissociation of this protein with SARA and the association with the family member SMAD4. The association with SMAD4 is important for the translocation of this protein into the nucleus, where it binds to target promoters and forms a transcription repressor complex with other cofactors. This protein can also be phosphorylated by activin type 1 receptor kinase, and mediates the signal from the activin. Alternatively spliced transcript variants have been observed for this gene.
ImmunogenSynthetic Peptide. A phospho specific peptide corresponding to residues surrounding T220 of human SMAD2.
Other NamesJV18, MADH2, MADR2, JV18-1, hMAD-2, hSMAD2, MGC22139, MGC34440, Mad-related protein 2, Mothers DPP homolog 2, Mothers decapentaplegic homolog 2, Smad 2, MAD homolog 2, SMAD family member 2, Smad2, SMAD3, MADH3, Mothers decapentaplegic homolog 3, MAD homolog 3, Mad3, Mothers DPP homolog 3, hMAD-3, JV15-2, SMAD family member 3, SMAD 3, hSMAD3, V18, Mothers against, JV18, JV18, JV18, JV18, MADH2, MADH2, MADH2, MADH2, MADR2, MADR2, MADR2, MADR2, JV18-1, JV18-1, JV18-1, JV18-1, hMAD-2, hMAD-2, hMAD-2, hMAD-2, hSMAD2, hSMAD2, hSMAD2, hSMAD2, MGC22139, MGC22139, MGC22139, MGC22139, MGC34440, MGC34440, MGC34440, MGC34440, Mad-related protein 2, Mad-related protein 2, Mad-related protein 2, Mad-related protein 2, Mothers DPP homolog 2, Mothers DPP homolog 2, Mothers DPP homolog 2, Mothers DPP homolog 2, Mothers decapentaplegic homolog 2, Mothers decapentaplegic homolog 2, Mothers decapentaplegic homolog 2, Mothers decapentaplegic homolog 2, Smad 2, Smad 2, Smad 2, Smad 2, MAD homolog 2, MAD homolog 2, MAD homolog 2, MAD homolog 2, SMAD family member 2, SMAD family member 2, SMAD family member 2, SMAD family member 2, Smad2, Smad2, Smad2, Smad2, SMAD3, SMAD3, SMAD3, SMAD3, MADH3, MADH3, MADH3, MADH3, Mothers decapentaplegic homolog 3, Mothers decapentaplegic homolog 3, Mothers decapentaplegic homolog 3, Mothers decapentaplegic homolog 3, MAD homolog 3, MAD homolog 3, MAD homolog 3, MAD homolog 3, Mad3, Mad3, Mad3, Mad3, Mothers DPP homolog 3, Mothers DPP homolog 3, Mothers DPP homolog 3, Mothers DPP homolog 3, hMAD-3, hMAD-3, hMAD-3, hMAD-3, JV15-2, JV15-2, JV15-2, JV15-2, SMAD family member 3, SMAD family member 3, SMAD family member 3, SMAD family member 3, SMAD 3, SMAD 3, SMAD 3, SMAD 3, hSMAD3, hSMAD3, hSMAD3, hSMAD3, V18, V18, V18, V18, Mothers against, Mothers, Mothers, Mothers against
Gene, Accession #SMAD2, Gene ID: 4087, UniProt: Q15796
Catalog #abx000321
Priceplease inquire
Order / More InfoMothers Against Decapentaplegic Homolog 2 Phospho-Thr220 (SMAD2 pT220) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
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