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Antigenic Specificity | COX4I1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 100 µL |
Concentration | 0.38 mg/mL |
Applications | Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin-embedded Sections), Immunoprecipitation, Western Blotting |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Product Characteristics: Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. Cellular Localization: Mitochondrion inner membraneTarget Information: Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes isoform 2 of subunit IV. Isoform 1 of subunit IV is encoded by a different gene, however, the two genes show a similar structural organization. Subunit IV is the largest nuclear encoded subunit which plays a pivotal role in COX regulation. [provided by RefSeq, Jul 2008]. |
Immunogen | Recombinant protein encompassing a sequence within the center region of human COX4. The exact sequence is proprietary. |
Other Names | COX4|COX4-1|COXIV|COX IV-1|cytochrome c oxidase polypeptide IV|cytochrome c oxidase subunit 4 isoform 1|mitochondrial|cytochrome c oxidase subunit 4I1|COX4I1|Cytochrome C Oxidase Subunit IV Isoform 1|mg:bb02d03|zgc:110058|GB20012|cytochrome c oxidase subunit 4 isoform 1, mitochondrial|LOC412396|OXPHOS complex IV subunit IV|LOC780848|BMEII0322|RSal33209_1582|cytochrome c oxidase subunit IV|SJAG_00976|HMPREF0733_11926|AL024441|Cox4a|cytochrome c oxidase|subunit IVa|subunit 4a|subunit IV|cytochrome c oxydase subunit 4|cytochrome c oxidase IV subunit|cytochrome c oxidase subunit IV isoform 1 S homeolog|cox4i1.S|BcDNA:AT07685|CG10396|COX IV|CX41|CX42|DmelCG10396|IV|CG10396 gene product from transcript CG10396-RB|CG10396-PA|CG10396-PB|COX4L-PA|COX4L-PB|cytochrome c oxidase subunit 4-like|COX4L |
Gene, Accession # | Gene ID: 1327 |
Catalog # | ABIN2855069 |
Price | $466.18 |
Order / More Info | COX4I1 Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |