TRPV4 Antibody from ANTIBODIES-ONLINE GmbH

Search, find, compare suppliers for anti-TRPV4 antibody, protein, ELISA kits.

Edit 
Antigenic SpecificityTRPV4
Clonepolyclonal
Host SpeciesSheep
Reactive Speciesmouse
Isotypen/a
Formatunconjugated
Size100 µL
Concentrationn/a
ApplicationsImmunohistochemistry, Western Blotting
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionProduct Characteristics: TRPV4 is a cation-selective channel, activated in response to systemic osmotic pressure.Function: Non-selective calcium permeant cation channel probably involved in osmotic sensitivity and mechanosensitivity. Activation by exposure to hypotonicity within the physiological range exhibits an outward rectification. Also activated by low pH, citrate and phorbol esters. Increase of intracellular Ca(2+) potentiates currents. Channel activity seems to be regulated by a calmodulin-dependent mechanism with a negative feedback mechanism.Subcellular location: Membrane, Multi-pass membrane protein.Tissue specificity: Expressed lung, spleen, kidney, testis, fat, and at very low levels in trigeminal ganglia. Also known as: Transient receptor potential cation channel subfamily V member 4, TrpV4, osm-9-like TRP channel 4, OTRPC4, Vanilloid receptor-like channel 2, Vanilloid receptor-like protein 2, Vanilloid receptor-related osmotically-activated channel, VR-OAC, Transient receptor potential protein 12, TRP12, Trp12, VRL-2, VROAC, OTRPC4, VR-OAC, MGC150050, 0610033B08Rik, Trp12, Vrl2, Vroac.Target Information: This gene encodes a member of the OSM9-like transient receptor potential channel (OTRPC) subfamily in the transient receptor potential (TRP) superfamily of ion channels. The encoded protein is a Ca2+-permeable, nonselective cation channel that is thought to be involved in the regulation of systemic osmotic pressure. Mutations in this gene are the cause of spondylometaphyseal and metatropic dysplasia and hereditary motor and sensory neuropathy type IIC. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010].
ImmunogenA synthetic peptide from mouse TRPV4 conjugated to an immunogenic carrier protein was used as the immunogen.
Other NamesVR-OAC|transient receptor potential cation channel subfamily V member 4|vanilloid receptor-related osmotically activated channel protein|TRPV4|Transient Receptor Potential Cation Channel, Subfamily V, Member 4|0610033B08Rik|OTRPC4|Trp12|VRL-2|VROAC|osm-9-like TRP channel 4|osmosensitive transient receptor potential channel 4|transient receptor potential protein 12|vanilloid receptor-like channel 2|vanilloid receptor-like protein 2|vanilloid receptor-related osmotically-activated channel|CMT2C|HMSN2C|SMAL|SPSMA|SSQTL1|VRL2|OSM9-like transient receptor potential channel 4|vanilloid receptor-related osmotically activated channel|transient receptor potential cation channel|subfamily 5|member 4|vanilloid receptor-related osmotically activated channel (Vroac)|wu:fp52e02|subfamily V|transient receptor potential cation channel subfamily V member 4-like
Gene, Accession #Gene ID: 63873
Catalog #ABIN351279
Price$454.67
Order / More InfoTRPV4 Antibody from ANTIBODIES-ONLINE GmbH
Product Specific Referencesn/a
ANTIBODIES-ONLINE GmbH
ANTIBODIES-ONLINE GmbH
ANTIBODIES-ONLINE GmbH
Schloss-Rahe-Str. 15
52072 Aachen GERMANY
P: +49 (0)241 95 163 153
F: +49 (0)241 95 163 155

info@antibodies-online.com
Orders: orders@antibodies-online.com
Technical Support: support@antibodies-online.com

https://www.antibodies-online.com

Profile of ANTIBODIES-ONLINE GmbH
Return to Antibodies

© 1980 - 2019 Linscott's Directory, Linscott's USA. All rights reserved.