s100b Antibody from ANTIBODIES-ONLINE GmbH

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Antigenic Specificitys100b
Clone9A11B9
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
Formatunconjugated
Size0.1 mL
Concentrationn/a
ApplicationsELISA, Immunohistochemistry, Western Blotting
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DescriptionProduct Characteristics: S100B (S100 calcium binding protein B) is a member of the S100 family of proteins containing 2 EF-hand calcium binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S-100 proteins and parvalbumin proteins are each expressed in neural tissues. In addition, S100B are present in a variety of other tissues, and calbindin is present in intestine and kidney. Parvalbumin B is found in many tumor tissues as well as in the organ of Corti. Calbindin, S-100 proteins and parvalbulmins have all been detected in leydig cells and the testis. These proteins are thought to play a role in hormone production and spermatogenesis. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.Synonyms: NEF, S100, S100betaTarget Information: The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21, however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes. [provided by RefSeq, Jul 2008].
ImmunogenPurified recombinant fragment of S100B expressed in E. Coli.
Other NamesNEF|S100|S100-B|S100beta|S-100 calcium-binding protein|beta chain|S-100 protein subunit beta|S100 calcium-binding protein|beta (neural)|protein S100-B|S100 calcium binding protein B|S100B|S100P|S-100 protein beta chain|S100 calcium-binding protein B|S100 calcium-binding protein beta (neural)|S100 protein|beta polypeptide|neural|AI850290|Bpb|S100 protein, beta polypeptide, neural|S100 calcium binding protein|beta|S-100 calcium-binding protein beta subunit|si:dkey-110p14.2|wu:fq18b10|zgc:92776|S100 calcium binding protein, beta (neural)
Gene, Accession #Gene ID: 6285
Catalog #ABIN966987
Price$627
Order / More Infos100b Antibody from ANTIBODIES-ONLINE GmbH
Product Specific ReferencesPubMed: 15143181
ANTIBODIES-ONLINE GmbH
ANTIBODIES-ONLINE GmbH
ANTIBODIES-ONLINE GmbH
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