53BP1 Antibody from BIOLEGEND

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Antigenic Specificity53BP1
CloneW17184B
Host SpeciesRat
Reactive Specieshuman, mouse
IsotypeIgG2a, κ
Formatpurified
Size100 µg
Concentrationn/a
ApplicationsWestern Blot (WB), ICC
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DescriptionPurified anti-53BP1. p53-binding protein 1 (53BP1) was first discovered as an interacting partner of p53 tumor suppressor protein in a yeast two-hybrid screening. 53BP1 binds to p53 through a BRCA1 C-terminal (BRCT) domain and enhances p53-dependent transcriptional activation. 53BP1 has been studied extensively for its function in the regulation of DNA double-strand break (DSB) repair pathway. Additionally, it promotes non-homologous end joining (NHEJ) while inhibiting homologous recombination (HR) by preventing DNA
ImmunogenPartial recombinant human 53BP1 protein.
Other NamesTumor Protein P53 Binding Protein 1, TP53-Binding Protein 1, P53-Binding Protein 1, P53BP1, Tumor Suppressor P53-Binding Protein 1, TDRD30, P202
Gene, Accession #Gene ID: 7158
Catalog #933002
Price$253
Order / More Info53BP1 Antibody from BIOLEGEND
Product Specific Referencesn/a
BIOLEGEND
BIOLEGEND
BIOLEGEND
8999 BioLegend Way
San Diego CA 92121
P: (858) 455-9588
P: 1-877-Bio-Legend (246-5343)
F: (858) 455-9587

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