Beclin-1 Antibody from BIOLEGEND

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Antigenic SpecificityBeclin-1
CloneO93F3
Host SpeciesMouse
Reactive Specieshuman, rat, mouse
IsotypeIgG1, κ
Formatpurified
Size100 µg
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionPurified anti-Beclin-1. Beclin-1 plays a central role in autophagy and is involved in autophagosome formation. It acts as core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate. Beclin-1 is necessary for the initiation of autophagy, and it has been shown to be reduced in the brains of patients with Alzheimer's disease. Reduced Beclin-1 levels lead to decreased autophagy, the accumulation of Aβ peptides, and neurodegeneration in mouse models of Alzheimer?s disease.
ImmunogenFull length recombinant human Beclin-1 protein (NP_003757) produced in HEK293T cells
Other NamesATG6 Autophagy Related 6 Homolog, VSP30
Gene, Accession #Gene ID: 8678
Catalog #849702
Price$288
Order / More InfoBeclin-1 Antibody from BIOLEGEND
Product Specific Referencesn/a
BIOLEGEND
BIOLEGEND
BIOLEGEND
8999 BioLegend Way
San Diego CA 92121
P: (858) 455-9588
P: 1-877-Bio-Legend (246-5343)
F: (858) 455-9587

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