MAP2 Antibody from BIOLEGEND

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Antigenic SpecificityMAP2
Host SpeciesChicken
Reactive Specieshuman, rat, mouse, bovine
Size50 µL
ApplicationsIHC-P, Western Blot (WB)
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DescriptionPurified anti-MAP2.

Microtubules are 25nm diameter protein rods found in most kinds of eukaryote cells. They are polymerized from a dimeric subunit made of one α subunit and one β tubulin subunit. Microtubules are associated with a family of proteins called microtubule associated proteins (MAPs), which includes the protein τ (tau) and a group of proteins referred to as MAP1, MAP2, MAP3, MAP4 and MAP5. MAP2 is made up of two about 280kD apparent molecular weight bands referred to as MAP2a and MAP2b. A third lower molecular weight form, usually called MAP2c, corresponds to a pair of protein bands running at about 70 kD on SDS-PAGE gels. All these MAP2 forms are derived from a single gene by alternative transcription, and all share a C-terminal sequence which includes either three or four microtubule binding peptide sequences, which are very similar to those found in the related microtubule binding protein τ (tau). MAP2 isoforms are expressed only in neuronal cells and specifically in the perikarya and dendrites of these cells. Antibodies to MAP2 are therefore excellent markers on neuronal cells, their perikarya and neuronal dendrites. In contrast τ (tau) is found predominantly in neuronal axons.

ImmunogenThis antibody was made against MAP2 in chickens.
Other NamesMicrotubule-associated protein 2, MAP-2
Gene, Accession #Gene ID: 4133
Catalog #822501
Order / More InfoMAP2 Antibody from BIOLEGEND
Product Specific ReferencesPubMed: 20185826, 27756764, 29554128, 29861287, 30737131, 29861287, 32679064, 33016621
8999 BioLegend Way
San Diego CA 92121
P: (858) 455-9588
P: 1-877-Bio-Legend (246-5343)
F: (858) 455-9587

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