SHP-2 Antibody from BIOLEGEND

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Antigenic SpecificitySHP-2
Host SpeciesMouse
Reactive Specieshuman, mouse
IsotypeIgG1, κ
Size100 µg
ApplicationsWestern Blot (WB)
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DescriptionPurified anti-SHP-2.

Src homology-2-containing protein tyrosine phosphatase 2 (SHP-2) protein, encoded by PTPN11 gene, is a well-known oncogenic protein tyrosine phosphatase. SHP-2 regulates cellular functions by dephosphorylating targets downstream of PD1, EGFRvIII, HGF receptor, and cytokine receptors. Cellular processes controlled by SHP-2 include mitotic cycle, cell growth, differentiation, and oncogenesis. SHP-2 has been recognized as a potential therapeutic target for cancers including breast cancer, lung cancer, leukemia, gastric cancer, and oral cancer.

ImmunogenSynthetic peptide from human SHP-2
Other NamesCFC, NS1, JMML, SHP2, BPTP3, PTP2C, METCDS, PTP-1D, SH-PTP2, SH-PTP3, Syp, Protein Tyrosine Phosphatase Non-Receptor Type 11, SH2 Domain-Containing Protein Tyrosine Phosphatase 2
Gene, Accession #Gene ID: 5781
Catalog #948202
Order / More InfoSHP-2 Antibody from BIOLEGEND
Product Specific Referencesn/a
8999 BioLegend Way
San Diego CA 92121
P: (858) 455-9588
P: 1-877-Bio-Legend (246-5343)
F: (858) 455-9587

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