CD107a Antibody from BIOLEGEND

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Antigenic SpecificityCD107a
CloneH4A3
Host SpeciesMouse
Reactive Specieshuman, African green, baboon, chimpanzee, cynomolgus, pigtailed macaque, rhesus
IsotypeIgG1, κ
FormatBrilliant Violet 711™ conjugate
Size100 tests
Concentrationn/a
ApplicationsFlow Cytometry (FC)
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionBrilliant Violet 711™ anti-human CD107a (LAMP-1). CD107a, also known as Lysosome-Associated Membrane Protein 1 (LAMP-1) or LGP-120, is a 110-140 kD type I membrane glycoprotein. Mature CD107a is heavily glycosylated from a 40 kD core protein. This molecule is located on the luminal side of lysosomes. Upon activation, CD107a is transferred to the cell membrane surface of activated platelets, activated lymphocytes, macrophages, epithelial cells, endothelial cells, and some tumor cells. CD107a has been suggested to play a role in the protection of lysosomal membrane from lysosomal hydrolases which is involved in cell adhesion and regulation of tumor metastasis, and mediates autoimmune disease progression. CD107a is a ligand for galaptin and E-selectin. Surface expression of LAMP-1 has been shown to correlate with CD8+ T cell and NK cell cytotoxicity.
ImmunogenHuman adult adherent peripheral blood cells
Other NamesLAMP1, LGP-120
Gene, Accession #Gene ID: 3916
Catalog #328640
Price$390
Order / More InfoCD107a Antibody from BIOLEGEND
Product Specific ReferencesPubMed: 21266579,21998199,22718823,24248359
BIOLEGEND
BIOLEGEND
BIOLEGEND
9727 Pacific Heights Blvd.
San Diego CA 92121
P: (858) 455-9588
P: 1-877-Bio-Legend (246-5343)
F: (858) 455-9587

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