CD195 Antibody from BIOLEGEND

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Antigenic SpecificityCD195
Host SpeciesRat
Reactive Specieshuman
IsotypeIgG2b, κ
FormatBrilliant Violet 785™ conjugate
Size100 tests
ApplicationsFlow Cytometry (FC)
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionBrilliant Violet 785™ anti-human CD195 (CCR5). CD195, also known as CCR5, is a 45 kD G protein-coupled seven transmembrane CC-chemokine receptor. It binds to MIP-1α, MIP-1β, and RANTES and is expressed on a subset of T cells and monocytes. CCR5 mediates an intracellular signal thought to induce cell differentiation and proliferation. CCR5 has also been shown to act as a co-receptor for R5 HIV-1 cell entry; modification of CCR5 by sulfation contributes to the efficiency of HIV-1 entry. Studies have shown CCR5 to play a role in a variety of other human diseases, ranging from infectious and inflammatory diseases to cancer.
ImmunogenHuman CCR5 transfectants
Other NamesCCR5, C-C chemokine receptor type 5, HIV-1 fusion co-receptor
Gene, Accession #Gene ID: 1234
Catalog #359132
Order / More InfoCD195 Antibody from BIOLEGEND
Product Specific Referencesn/a
9727 Pacific Heights Blvd.
San Diego CA 92121
P: (858) 455-9588
P: 1-877-Bio-Legend (246-5343)
F: (858) 455-9587

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