Gephyrin Antibody from BIOLEGEND

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Antigenic SpecificityGephyrin
Host SpeciesMouse
Reactive Specieshuman, mouse, rat
IsotypeIgG2a, κ
Size100 µg
ApplicationsWestern Blot (WB), IHC-P
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DescriptionPurified anti-Gephyrin. Gephyrin (GPHN) is a scaffold protein that anchors glycine and GABA receptors to the tubulin cytoskeleton in the postsynaptic terminal of inhibitory synapses. Gephyrin's function as a scaffolding protein is regulated at transcriptional and translational levels, which impact the formation and plasticity of GABAergic synapses, as well as the overall strength of GABAergic transmission. Low levels of gephyrin in temporal lobe correspond to reduced inhibitory signals and correlate with temporal lobe epilepsy.
ImmunogenHuman recombinant gephyrin expressed in human HEK293T cells.
Other NamesGPHN, Gephyrin
Gene, Accession #Gene ID: 10243, 268566, 64845
Catalog #856102
Order / More InfoGephyrin Antibody from BIOLEGEND
Product Specific Referencesn/a
9727 Pacific Heights Blvd.
San Diego CA 92121
P: (858) 455-9588
P: 1-877-Bio-Legend (246-5343)
F: (858) 455-9587

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