P62 (SQSTM1) Antibody from BIOLEGEND

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Antigenic SpecificityP62 (SQSTM1)
Clone1B5.H9
Host SpeciesMouse
Reactive Specieshuman, mouse, rat
IsotypeIgG1, κ
Formatpurified, azide-free
Size100 µL
Concentrationn/a
ApplicationsIHC-P, Western Blot (WB), ICC
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionPurified (azide-free) anti-p62 (SQSTM1). The p62 protein, also called sequestosome 1 (SQSTM1), is a ubiquitin-binding scaffold protein that colocalizes with ubiquitinated protein aggregates in many neurodegenerative diseases and proteinopathies of the liver. The protein is able to polymerize via an N-terminal PB1 domain and can interact with ubiquitinated proteins via the C-terminal UBA domain. Also, p62/SQSTM1 binds directly to LC3 and GABARAP family proteins via a specific sequence motif. The protein is itself degraded by autophagy a
ImmunogenThis monoclonal antibody was raised against a peptide sequence corresponding to amino acids 201-212 of the human SQSTM 1 (isoform 1) protein conjugated to KLH.
Other NamesP60, p62, A170, OSIL, PDB3, ZIP3, p62B, sequestosome-1, oxidative stress-induced-like ubiquitin-binding protein p62
Gene, Accession #Gene ID: 8878
Catalog #814801
Price$275
Order / More InfoP62 (SQSTM1) Antibody from BIOLEGEND
Product Specific ReferencesPubMed: 30760704, 31831743
BIOLEGEND
BIOLEGEND
BIOLEGEND
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