PICK1 Antibody from BIOLEGEND

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Antigenic SpecificityPICK1
CloneL20/8
Host SpeciesMouse
Reactive Specieshuman, mouse, rat
IsotypeIgG2a
Formatpurified, azide-free
Size25 µL
Concentrationn/a
ApplicationsWestern Blot (WB)
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionPurified (azide-free) anti-PICK1.

Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate ASIC1/ASIC3 channel. Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex; the function is competetive with nucleation promoting factors and is linked to neuronal morphology regulation and AMPA receptor (AMPAR) endocytosis. Via interaction with the Arp2/3 complex involved in regulation of synaptic plasicity of excitatory synapses and required for spine shrinkage during long-term depression (LTD). Involved in regulation of astrocyte morphology, antagonistic to Arp2/3 complex activator WASL/N-WASP function. (Uniprot)

ImmunogenThis monoclonal antibody was raised against a fusion protein corresponding to amino acids 10-130 of rat PICK1 protein.
Other NamesPRKCA-binding protein, protein interacting with C kinase 1, protein kinase C-alpha-binding protein, protein that interacts with C kinase 1, protein kinase C, alpha binding protein, PRKCABP
Gene, Accession #Gene ID: 84591
Catalog #830902
Price$70
Order / More InfoPICK1 Antibody from BIOLEGEND
Product Specific ReferencesPubMed: 32840212, 31704539, 31315049, 32317027, 32294450, 31607563, 31914388, 31794381, 32640235, 32238932, 33060836, 1639395, 25112282, 26604147, 22492355, 17525177, 26658466, 26720731, 26516211, 25535268, 26554594, 25146370, 26879757, 26899176, 26939553, 26958831, 27053772, 27094546, 27120160, 27049876, 27214567, 27279226, 27142930, 27246713, 27322420, 27334688, 27310015, 27403992, 27411104, 27170656, 27471043, 27445154, 27396343, 27556059, 27581449, 27179434, 27605619, 27694961, 27703173, 27810911, 27688094, 27861587, 27861587, 27861592, 27848932, 27829154, 27911847, 28013231, 28137726, 28013290, 28139695, 28092684, 28139645, 28233843, 28253236, 28253236, 28752164, 28591194, 28829770, 28752164, 28591194, 29435496, 29414415, 29600249, 29698519, 29745900, 29789581, 29961578, 30384131, 29414415, 30244870, 29779941, 29249360, 30130681, 30067988, 30344048, 30095408, 30392794, 29395907, 29212816, 29439167, 30067988, 30258099, 28288114, 28541657, 29233477, 29258872, 30201687, 30485816, 30566428, 30657775, 30659230, 30699348, 28703293, 28993200, 29077851, 30302725, 30455455, 30917318, 30964447, 31033435, 31097699, 31116980, 31124784, 28973407, 31318893, 29868845, 31094678, 30342961, 28703293, 31203451, 30302725, 31037510, 31097699, 31239441, 29760764, 30139844, 30964447, 28993200, 30811996, 31116980, 31242417, 30924151, 28728023, 30246867, 29193451, 31242417, 28578927, 30811996, 30404017, 29980930, 28196805, 30796637, 31037510, 30924151, 31203451, 30139844, 29945866, 30217809, 31239441, 31521111, 29760764, 31453803, 30246867, 28475893, 31511512, 29033352, 31094678, 30731422, 31390572, 30661738, 30695697, 31124784, 31375262, 30861584, 30095408, 30344048, 30067988, 30130681, 29249360, 30246867, 29779941, 30244870, 29414415, 30384131, 29961578, 29395907, 30392794, 30225841, 30523785, 29033352, 28475893, 28965765, 28803920, 28472654, 28132835, 28507510, 28803920, 29311838, 29977079, 30095408, 30344048, 30392794, 30656621, 31168097, 31191687, 31353074, 31390572, 31666641, 31868578, 31877727, 31877913, 31915063, 32103003, 30661738, 32231223, 32228681, 32245946, 32258211, 31096043, 31543471, 30735633, 31693895, 31665628, 31315048, 30554998, 30695697, 30449657, 32211407, 28111201, 30578296, 30626697, 32245946, 29029025, 30304678, 30692224
BIOLEGEND
BIOLEGEND
BIOLEGEND
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