SOD (EC) Antibody from BIORBYT LTD.

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Antigenic SpecificitySOD (EC)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatphycoerythrin (RPE) conjugate
Size100 ug
Concentration1 mg/ml
ApplicationsICC, WB
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DescriptionRabbit polyclonal to SOD (RPE). Superoxide dismutase (SOD) is an endogenously produced intracellular enzyme present in almost every cell in the body. It works by catalyzing the dismutation of the superoxide radical O2 to O2 and H2O2, which are then metabolized to H2O and O2 by catalase and glutathione peroxidase (2, 5). In general, SODs play a major role in antioxidant defense mechanisms. There are three types of SOD in mammalian cells. One form (SOD1) contains Cu and Zn ions as a homodimer and exists in the cytoplasm. The two subunits of 16 kDa each are linked by two cysteines forming an intra-subunit disulphide bridge. The second form (SOD2) is a manganese containing enzyme and resides in the mitochondrial matrix. It is a homotetramer of 80 kDa. The third form (SOD3 or EC-SOD) is like SOD1 in that it contains Cu and Zn ions, however it is distinct in that it is a homotetramer, with a mass of 30 kDA and it exists only in the extra-cellular space. SOD3 can also be distinguished by its heparin-binding capacity..
ImmunogenPeptide corresponding to AA 227-236 of human EC SOD
Other NamesEC SOD, EC-SOD, Extracellular superoxide dismutase [Cu Zn], Extracellular superoxide dismutase [Cu-Zn], Extracellular superoxide dismutase, Extracellular superoxide dismutase precursor, MGC20077, SOD 3, SOD3, SODE_HUMAN, Superoxide dismutase 3 extracellular
Gene, Accession #Gene ID: 6649, UniProt: P08294
Catalog #orb151535
Price$614
Order / More InfoSOD (EC) Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
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F: +44(0)1223 280 240

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