SUR1 Antibody from BIORBYT LTD.

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Antigenic SpecificitySUR1
CloneS289-16
Host SpeciesMouse
Reactive Specieshamster, human, mouse, rat
IsotypeIgG1
Formatbiotin conjugate
Size100 ug
Concentration1 mg/ml
ApplicationsICC, WB, IHC
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DescriptionMouse monoclonal to SUR1 (Biotin). Sulfonylurea receptors (SUR) are membrane proteins which are the molecular targets of the sulfonylurea class of anti-diabetic drugs whose mechanism of action is to promote insulin release from pancreatic beta cells. More specifically, SUR proteins are subunits of the inward-rectifier potassium ion channels Kir6. x (6. 1 and 6. 2). The association of four Kir6. x and four SUR subunits form an ion conducting channel commonly referred to as the KATP channel. The primary function of the sulfonylurea receptor is to sense intracellular levels of the nucleotides ATP and ADP and in response facilitate the open or closing its associated Kir6. x potassium channel. Hence the KATP channel monitors the energy balance within the cell..
ImmunogenFusion protein amino acids 1548-1582 (cytoplasmic C-terminus) of rat SUR1
Other NamesAM60008PU-N, ABC36, Abcc8, ATP binding cassette sub family C member 8, HHF1, HRINS, MRP8, PHHI, SUR, SUR1, Sulfonylurea receptor (hyperinsulinemia), ATP binding cassette sub family C (CFTR/MRP) member 8, ATP binding cassette transporter sub family C member 8 (1), ATP-binding cassette sub-family C member 8, HI, PHHI, Sulfonylurea receptor 1, SUR1delta2, TNDM2
Gene, Accession #UniProt: Q09429, Gene ID: 25559
Catalog #orb149980
Priceplease inquire
Order / More InfoSUR1 Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
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Swann Road
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P: +44 (0)1223 859 353
F: +44(0)1223 280 240

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