Pol II Antibody from BIOSS ANTIBODIES

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Antigenic SpecificityPol II
Clone3A27
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
FormatProtein A purified
Size50ug
Concentration1ug/ul
ApplicationsWB, ELISA, IF(ICC), ChIP
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DescriptionPol II (3A27) Monoclonal Antibody • Target background: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Forms the polymerase active center together with the second largest subunit. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB1 is part of the core element with the central large cleft, the clamp element that moves to open and close the cleft and the jaws that are thought to grab the incoming DNA template. At the start of transcript
ImmunogenMonoclonal antibody raised in mouse against the YSPTSPS repeat in the B1 subunit of RNA polymerase II
Other NamesPOLR2A, RPB1, POLR2, RPOL2
Gene, Accession #Gene ID: 5430, SwissProt: P24928
Catalog #bsm-53004M
Price$388
Order / More InfoPol II Antibody from BIOSS ANTIBODIES
Product Specific Referencesn/a
BIOSS ANTIBODIES
BIOSS ANTIBODIES
BIOSS ANTIBODIES
500 West Cummings Park, Suite 6500
Woburn MA 01801
P: 1-800-501-7654

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