BACE2 Antibody from BIOVISION, INC.

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Antigenic SpecificityBACE2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size100 µg
Concentration05 mg/ml
ApplicationsWestern blot
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DescriptionPolyclonal antibody to detect BACE2/Asp1 in human samples. Accumulation of the amyloid-beta (Abeta) plaque in the cerebral cortex is a critical event in the pathogenesis of Alzheimer's disease. Abeta peptide is generated by proteolytic cleavage of the beta-amyloid protein precursor (APP) at beta- and gamma-sites by proteases. The long-soµght beta-secretase was recently identified by several groups independently and designated beta-site APP cleaving enzyme (BACE) and aspartyl protease 2 (Asp2). A BACE homolog was recently cloned and designated BACE2, Asp1, DRAP (for Down region aspartic protease), and memapsin 1. BACE2 also cleaves APP at beta-site and at a different site within Abeta. BACE2 locates on chromosome 21q22.3, the so-called
ImmunogenA synthetic peptide corresponding to the amino acids 44 to 59 of human BACE2.
Other NamesBACE2, Asp1
Gene, Accession #Gene ID: 25825, Accession: Q9Y5Z0
Catalog #6102-100
Price$295
Order / More InfoBACE2 Antibody from BIOVISION, INC.
Product Specific Referencesn/a
BIOVISION, INC.
BIOVISION, INC.
BIOVISION, INC.
155 S. Milpitas Boulevard
Milpitas CA 95035
P: 408-493-1800
P: 800-891-9699
F: 408-493-1801

support@biovision.com

http://www.biovision.com

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