Integrin beta-1 Antibody from BIOVISION, INC.

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Antigenic SpecificityIntegrin beta-1
CloneRM285
Host SpeciesRabbit
Reactive Specieshuman
IsotypeIgG
Formataffinity purified
Size50 µl
Concentrationn/a
ApplicationsWB, IHC. RUO
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DescriptionIntegrin alpha-V/beta-1 is a receptor for vitronectin. Beta-1 integrins recognize the sequence R-G-D in a wide array of ligands. Isoform 2 interferes with isoform 1 resulting in a dominant negative effect on cell adhesion and migration (in vitro). When associated with alpha-7/beta-1 integrin, regulates cell adhesion and laminin matrix deposition. Involved in promoting endothelial cell motility and angiogenesis. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process and the formation of mineralized bone nodules. May be involved in up-regulation of the activity of kinases such as PKC via binding to KRT1.
ImmunogenA peptide corresponding to the residues in human CD29 (Integrin beta-1).
Other NamesIntegrin beta-1, Fibronectin receptor subunit beta, GPIIA, CD29, FNRB, MDF2, MSK12
Gene, Accession #Gene ID: 3688, Accession: P05556
Catalog #A1598-50
Price$285
Order / More InfoIntegrin beta-1 Antibody from BIOVISION, INC.
Product Specific Referencesn/a
BIOVISION, INC.
BIOVISION, INC.
BIOVISION, INC.
155 S. Milpitas Boulevard
Milpitas CA 95035
P: 408-493-1800
P: 800-891-9699
F: 408-493-1801

support@biovision.com

http://www.biovision.com

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