TRPV4 Antibody from BOSTER BIO

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Antigenic SpecificityTRPV4
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Formatimmunogen affinity purified
Size100ug (sample available)
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DescriptionRabbit IgG polyclonal antibody for Transient receptor potential cation channel subfamily V member 4(TRPV4) detection. Tested with WB in Human;Mouse;Rat. No cross reactivity with other proteins. TRPV4(Transient Receptor Potential Cation Channel Subfamily V Member 4), also known as TRP12, OTRPC4 or VROAC, is a protein that in humans is encoded by the TRPV4 gene. This gene encodes TRPV4, a member of the OSM9-like transient receptor potential channel(OTRPC) subfamily in the transient receptor potential(TRP) superfamily of ion channels. By genomic sequence analysis, Liedtke et al.(2000) mapped the TRPV4 gene to chromosome 12q24.1. They mapped the mouse Trpv4 gene to distal chromosome 5 by radiation hybrid analysis. Wissenbach et al.(2000) found that hypoosmotic conditions rapidly activated TRP12, while hyperosmotic conditions inhibited the activity.Strotmann et al.(2000) showed that OTRPC4 was responsive to changes in extracellular osmolarity in the physiologically relevant range and was expressed in tissues exposed to changing osmotic environments.
ImmunogenA synthetic peptide corresponding to a sequence at the N-terminus of human TRPV4(113-133aa YRHHSSDNKRWRKKIIEKQPQ), identical to the related rat and mouse sequences.
Other NamesTransient receptor potential cation channel subfamily V member 4;TrpV4;Osm-9-like TRP channel 4;OTRPC4;Transient receptor potential protein 12;TRP12;Vanilloid receptor-like channel 2;Vanilloid receptor-like protein 2;VRL-2;Vanilloid receptor-related osmotically-activated channel;VR-OAC;TRPV4;VRL2, VROAC;
Gene, Accession #TRPV4, UniProt: Q9HBA0
Catalog #PA1979
Order / More InfoTRPV4 Antibody from BOSTER BIO
Product Specific Referencesn/a
3942 B Valley Ave
Pleasanton CA 94566
P: (888) 466-3604
F: (925) 215-2184

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