PARP (Cleaved) Antibody from CAYMAN CHEMICAL COMPANY

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Antigenic SpecificityPARP (Cleaved)
Clonemonoclonal
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2bκ
Formatunconjugated
Size1 ea
Concentrationn/a
ApplicationsFlow Cytometry, Western Blot
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DescriptionAntigen: synthetic peptide containing amino acids near the 214/215 cleavage site of human PARP • Isotype: IgG2bκ • Host: mouse • Cross Reactivity: (+) human PARP • Application(s): FC (intracellular) and WB • PARP is a 116 kDa nuclear chromatin-associated enzyme that is cleaved during apoptosis by caspase-3 into a 24 kDa fragment containing the DNA binding domain and an 89 kDa fragment containing the catalytic and automodification domains. The 24 kDa fragment irreversibly binds to DNA and may contribute to the irreversibility of apoptosis by blocking the access of DNA repair enzymes to DNA strand breaks.
Immunogensynthetic peptide containing amino acids near the 214/215 cleavage site of human PARP
Other Namespoly ADP ribose polymerase ADP-ribose DNA western blots immunoblotting WB flow cytometry intracellular antibodies FC blotting
Gene, Accession #n/a
Catalog #13557-1
Price$359.00
Order / More InfoPARP (Cleaved) Antibody from CAYMAN CHEMICAL COMPANY
Product Specific Referencesn/a
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640

Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com

http://www.caymanchem.com

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