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Antigenic Specificity | mAChR M2 |
Clone | B8E5 |
Host Species | Mouse |
Reactive Species | guinea pig, human, mouse, rat |
Isotype | IgG2a |
Format | purified |
Size | 50 µg |
Concentration | 100 µg/ml |
Applications | ELISA, Functional Assay, ICC/IF, IHC-Fr, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse anti-mAChR M2 monoclonal antibody [B8E5]. Monoclonal antibody B8E5 acts by functional dimerization of the receptor resulting in stabilization of the constitutive active receptor dimers and paradoxically induces a small decrease in carbachol affinity for the M2 receptor. It recognizes the pentapeptide VRTVE (aa 168-172) corresponding to the N-terminal part of the second extracellular loop of the human M2 receptor. |
Immunogen | Peptide VRTVEDGECYIQFFSNAAVTFGTAI(C): Human second extracellular loop residues 168-192 |
Other Names | CHRM2,HM2,cholinergic receptor muscarinic 2,mAChR M2,Muscarinic Acetylcholine Receptor 2 |
Gene, Accession # | Gene ID: 1129, UniProt: P08172 |
Catalog # | GTX54482 |
Price | $399 |
Order / More Info | mAChR M2 Antibody from GENETEX INC. |
Product Specific References | n/a |