GCLM Antibody from HUABIO INC.

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Antigenic SpecificityGCLM
Host SpeciesRecombinant Rabbit
Reactive Specieshuman, mouse, rat
Concentration1 mg/mL.
ApplicationsWB, ICC/IF, IHC, FC, IP
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DescriptionGamma-glutamylcysteine synthetase (γ-GCS) is the rate limiting enzyme for glutathione (L-gamma-glutamyl-L-cysteinylglycine, GSH) synthesis. GSH is ubiquitous in mammalian cells as a vital intra- and extracellular protective antioxidant. γ-GCS is a heterodimer of a heavy catalytic subunit and a light regulatory subunit that is responsive to inflammation, phenolic antioxidants, heat shock, oxidants and cytokines. The human gamma-GCS gene encoding the 367 amino acid catalytic subunit maps to chromosome 6p12. The human γ-GCS gene encoding the regulatory subunit maps to chromosome 1p22-p21. The two subunits of γ-GCS form a heterodimeric zinc metalloprotein that gains activity through formation of a reversible disulfide bond.
ImmunogenRecombinant protein
Other NamesGamma ECS regulatory subunit, Gamma-ECS regulatory subunit, Gamma-glutamylcysteine synthetase regulatory subunit, GCLM, GCS light chain, GLCLR, Glutamate cysteine ligase regulatory subunit, Glutamatecysteine ligase modifier subunit, Glutamatecysteine ligase regulatory subunit, GSC light chain, GSH0_HUMAN,
Gene, Accession #n/a
Catalog #ET1705-87
Order / More InfoGCLM Antibody from HUABIO INC.
Product Specific Referencesn/a

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