Integrin beta-1/CD29 Antibody from HUABIO INC.

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Antigenic SpecificityIntegrin beta-1/CD29
Host SpeciesRabbit
Reactive Specieshuman, mouse
Concentration1 mg/mL.
ApplicationsWB, IHC, FC
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DescriptionIntegrins are transmembrane receptors that mediate the attachment between a cell and its surroundings, such as other cells or the extracellular matrix (ECM). Integrins are obligate heterodimers containing two distinct chains, called the α (alpha) and β (beta) subunits. The molecular mass of the integrin subunits can vary from 90?kDa to 160?kDa. Beta subunits have four cysteine-rich repeated sequences. Both α and β subunits bind several divalent cations. Integrins have two main functions: Attachment of the cell to the ECM and signal transduction from the ECM to the cell. However, they are also involved in a wide range of other biological activities, including immune patrolling, cell migration, and binding to cells by certain viruses, such as adenovirus, echovirus, hantavirus, and foot and mouth disease viruses. Research studies have implicated β1 integrin in various activities including embryonic development, blood vessel, skin, bone, and muscle formation, as well as tumor metastasis and angiogenesis.
Other Namesbeta1 integrin, CD29, Fibronectin receptor subunit beta, FNRB, Glycoprotein IIa, GP IIa, GPIIA, Integrin beta-1, integrin VLA-4 beta subunit, Integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12), ITB1_HUMAN, ITGB1, MDF2, MSK12, OTTHUMP00000019420, Very late activation protein, beta polypeptide, VLA BETA, VLA-4 subunit beta, VLA-BETA, VLAB, VLAbeta,
Gene, Accession #n/a
Catalog #ER31001
Order / More InfoIntegrin beta-1/CD29 Antibody from HUABIO INC.
Product Specific Referencesn/a

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