Estrogen Receptor beta Antibody from INVITROGEN ANTIBODIES

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Antigenic SpecificityEstrogen Receptor beta
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpurified
Size50 µg
Concentrationn/a
ApplicationsImmunocytochemistry: 1:100, Immunofluorescence: 1:100, Immunohistochemistry (Frozen): 2-5 µg/mL, Immunohistochemistry (Paraffin): 2-5 µg/mL, Western Blot: 1 µg/mL
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DescriptionEstrogen Receptor beta Polyclonal Antibody. Estrogen Receptor beta (ER beta, NR3A2) protein is approximately 55kD, though multiple isoforms ranging from 36-59kD have been described. Human ER beta was initially cloned and characterized from testis. Estrogen Receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of nuclear receptors. The estrogen receptor is a ligand-activated transcription factor, that when bound to estrogen hormone, induces a conformational change that allows dimerization and binding to estrogen response elements (ERE) in DNA. When bound to EREs, ER can positively or negatively regulate gene transcription through the recruitment of coactivator or corepressor proteins. There are two different forms of
Immunogenn/a
Other NamesER Beta, ER, ESR2, ESR-Beta
Gene, Accession #Entrez: 13983, 2100, 25149; Uniprot: O08537, Q62986, Q92731
Catalog #PA1-313
Price$380
Order / More InfoEstrogen Receptor beta Antibody from INVITROGEN ANTIBODIES
Product Specific ReferencesPubMed: 10579363, 10623650, 11228250, 11344205, 11470188, 12163132, 12213896, 12810582, 15003201, 15314175, 15976006, 16153501, 16243798, 18184756, 18516675, 18562193, 18703142, 19415456, 20809984, 23868020, 26328009, 26328764, 27133732
INVITROGEN ANTIBODIES
INVITROGEN ANTIBODIES
INVITROGEN ANTIBODIES
by Thermo Fisher Scientific
81 Wyman Street
Waltham MA 02451
P: 800-678-5599
F: 800-331-2286

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