GAD65 Antibody from INVITROGEN ANTIBODIES

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Antigenic SpecificityGAD65
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpurified
Size100 µL
Concentrationn/a
ApplicationsImmunohistochemistry (Paraffin): 1:100-1:1000, Western Blot: 1:500-1:3000
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DescriptionGAD65 Polyclonal Antibody. GAD65 (glutamic acid decarboxylase-65) are present in autoimmune disorders such as insulin-dependent (type1) diabetes mellitus (IDDM), stiff man syndrome and polyendocrine autoimmune disease. Auto-antibodies to GAD65 are present in 60-70% of individuals with newly diagnosed IDDM and thus are important markers for disease activity. These auto-antibodies usually recognize conformation-dependent regions on GAD65 and rarely bind to the second isoform, GAD67. Auto-antibodies to GAD67 are found in only 15% of recent-onset IDDM patients and most of this binding can be blocked with GAD65, suggesting shared epitopes between the two isoforms of GAD.
Immunogenn/a
Other Names6330404F12Rik, GAD(65), Gad2, glutamic acid decarboxylase 2
Gene, Accession #Entrez: 14417, 24380, 2572; Uniprot: P48320, Q05329, Q05683
Catalog #PA5-77983
Price$381
Order / More InfoGAD65 Antibody from INVITROGEN ANTIBODIES
Product Specific Referencesn/a
INVITROGEN ANTIBODIES
INVITROGEN ANTIBODIES
INVITROGEN ANTIBODIES
by Thermo Fisher Scientific
81 Wyman Street
Waltham MA 02451
P: 800-678-5599
F: 800-331-2286

customerservice@lifetech.com
Technical Support: techsupport@lifetech.com

https://www.thermofisher.com

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