Sortilin Antibody from INVITROGEN ANTIBODIES

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Antigenic SpecificitySortilin
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpurified
Size100 µL
Concentrationlyophilized
ApplicationsELISA: 1:5,000, Immunohistochemistry: 1:1,000
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DescriptionSortilin Polyclonal Antibody. Sortilin functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Sortilin is required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR). It is also required for protein transport from the Golgi apparatus to the endosomes. Sortilin promotes neuronal apoptosis by mediating endocytosis of the proapoptotic precursor forms of BDNF (proBDNF) and NGFB (proNGFB). Also, Sortilin acts as a receptor for neurotensin.
Immunogenn/a
Other Namesneurotensin receptor 3
Gene, Accession #Entrez: 20661, 6272, 83576; Uniprot: O54861, Q6PHU5, Q99523
Catalog #PA1-18312
Price$381
Order / More InfoSortilin Antibody from INVITROGEN ANTIBODIES
Product Specific ReferencesPubMed: 29100377
INVITROGEN ANTIBODIES
INVITROGEN ANTIBODIES
INVITROGEN ANTIBODIES
by Thermo Fisher Scientific
81 Wyman Street
Waltham MA 02451
P: 800-678-5599
F: 800-331-2286

customerservice@lifetech.com
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