Zika Virus NS1 Antibody from INVITROGEN ANTIBODIES

Zika Virus NS1 Antibody from INVITROGEN ANTIBODIES
Antigenic SpecificityZika Virus NS1
CloneEA23
Host SpeciesMouse
Reactive Speciesn/a
IsotypeIgG1
Formatn/a
Size100 µg
Concentrationn/a
ApplicationsELISA: 1:20-1:200, Immunocytochemistry: 1:10-1:50, Immunofluorescence: 1:10-1:50
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DescriptionZika Virus NS1 Monoclonal Antibody (EA23). As a member of the Flaviviridae family, ZIKV has a single positive sense RNA genome, which is initially translated as a single polyprotein which is then cleaved post-transitionally into three structural proteins (C, PrM or M, and E) and seven nonstructural (NS) proteins (NS1, NS2A, NS2B, NS3, NS4A, NS4B and NS5)(1). The glycosated NS1 forms a homodimer inside the cells and is necessary for viral replication and late in infection (2). NS1 is also secreted into the extracellular space as a hexameric lipoprotein particle, which assists the virus in immune evasion and pathogenesis by interacting with components from both innate and adaptive immune systems as well as other host factors (1). Reference 1) Song, H.; Qi, J.; Haywood, J.; Shi, Y.; Gao, G.F. (2016). Nat. Struct. Mol. Biol. 23, 456-458. 2) Suthar, M.S., Diamond, M.S. & Gale, M. Jr. (2013). Nat. Rev. Microbiol. 11, 115-128.
Immunogenn/a
Other NamesZIKV NS1, ZIKV-NS1, Nonstructural protein 1, NS1
Gene, Accession #n/a
Catalog #MA5-24582
Price$309
Order / More InfoZika Virus NS1 Antibody from INVITROGEN ANTIBODIES
Product Specific Referencesn/a
INVITROGEN ANTIBODIES
INVITROGEN ANTIBODIES
INVITROGEN ANTIBODIES
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