PKCα pT497, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG

Search, find, compare suppliers for anti-PKCα pT497, Human antibody, protein, ELISA kits.

Edit 
Antigenic SpecificityPKCα pT497, Human
CloneREA821
Host SpeciesRecombinant Human
Reactive Specieshuman
IsotypeIgG1
Formatfluorescein (FITC) conjugate
Size100 tests in 200 µL
Concentration1:50
ApplicationsIntracellular flow cytometry
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionPKCα pT497 Antibody, anti-human, FITC, REAfinity™. Clone REA821 recognizes the PKCα antigen phosphorylated at threonine 497. PKCα has been reported to crossreact with PKCβ. PKCα is a serine- and threonine-specific protein kinase that can be activated by calcium and the second messenger diacylglycerol. It plays roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. PKCα is highly expressed in a number of cancer cells where it can acts as a tumor promoter and it is implicated in malignant phenotypes of several tumors such as gliomas and breast cancers. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca2+ handling in myocytes. | Additional information: Clone REA821 displays negligible binding to Fc receptors.
Immunogenn/a
Other NamesPRKCA, AAG6, PKC-alpha, PRKACA, PKC-A
Gene, Accession #Gene ID: 5578
Catalog #130-112-473
Price$270
Order / More InfoPKCα pT497, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesFinkenzeller, G. et al. (1990) Sequence of human protein kinase C alpha. Nucleic Acids Res. 18 (8): 2183. | Xu, H. et al. (2008) Protein kinase C alpha promotes angiogenic activity of human endothelial cells via induction of vascular endothelial growth factor. Cardiovasc. Res. 78 (2): 349-355.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

macs@miltenyibiotec.de

https://www.miltenyibiotec.com

Profile of MILTENYI BIOTEC B.V. & Co. KG
Return to Antibodies

© 1980 - 2024 Linscott's Directory, Linscott's USA. All rights reserved.