CD253, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD253, Mouse |
| Clone | REA1030 |
| Host Species | Recombinant Human |
| Reactive Species | mouse |
| Isotype | IgG1 |
| Format | allophycocyanin (APC) conjugate |
| Size | 30 µg in 200 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD253 Antibody, anti-mouse, APC, REAfinity™. Clone REA1030 recognizes the mouse CD253 antigen, a type 2 transmembrane protein also known as TNF-related apoptosis-inducing ligand (TRAIL), APO-2 ligand (APO-2L), or TNF ligand superfamily member 10 (TNFSF10). CD253 is expressed on a variety of cells of the innate and adaptive immune system, including natural killer (NK) cells. Often expression is induced or upregulated upon activation. CD253 can trigger apoptosis through trimerization of death receptor DR5 (TRAILR). | Additional information: Clone REA1030 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | TNFSF10, APO2L, Ly81, TL2, TRAIL |
| Gene, Accession # | Gene ID: 22035 |
| Catalog # | 130-117-561 |
| Price | $93 |
| Order / More Info | CD253, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Wiley, S. R. et al. (1995) Identification and characterization of a new member of the TNF family that induces apoptosis. Immunity 3 (6): 673-682. | Hofmann, K. (1999) The modular nature of apoptotic signaling proteins. Cell. Mol. Life Sci. 55 (8-9): 1113-1128. | Locksley, R. M. et al. (2001) The TNF and TNF receptor superfamilies: integrating mammalian biology. Cell 104 (4): 487-501. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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