CD11b, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityCD11b, Mouse
CloneREA592
Host SpeciesRecombinant Human
Reactive Speciesmouse, nonhuman primate, human
IsotypeIgG1
FormatVioBlue conjugate
Size30 µg in 200 µL
Concentration1:50
ApplicationsFlow cytometry
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DescriptionCD11b Antibody, anti-mouse, VioBlue®, REAfinity™. Clone REA592 recognizes the mouse CD11b antigen (Mac-1 α; integrin αM chain), which is part of the CD11b/CD18 heterodimer (Mac-1 α, Mβ2 integrin), also known as the C3 complement receptor. It functions as a receptor for complement (C3bi), fibrinogen, or clotting factor X. CD11b is expressed on monocytes, macrophages, and microglia. To a lower extent it is expressed on granulocytes, NK cells, CD5+ B-1 cells, and subsets of dendritic cells. Clone REA592 recognizes also the non-human primate and human CD11b antigen. | Additional information: Clone REA592 displays negligible binding to Fc receptors.
Immunogenn/a
Other Namesintegrin αM, Mac-1 α, Integrin alpha-M, CR3A
Gene, Accession #Gene ID: 3684, 16409
Catalog #130-113-810
Price$136
Order / More InfoCD11b, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesPahl, H. L. et al. (1992) Characterization of the myeloid-specific CD11b promoter. Blood 79 (4): 865-870. | Lebson, L. et al. (2010) Trafficking CD11b-positive blood cells deliver therapeutic genes to the brain of amyloid-depositing transgenic mice. J. Neurosci. 30 (29): 9651-9658. | Liu, T. et al. (2014) Gr-1+CD11b+ cells facilitate Lewis lung cancer recurrence by enhancing neovasculature after local irradiation. Sci Rep 4: 4833.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

macs@miltenyibiotec.de

https://www.miltenyibiotec.com

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