CD11b, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD11b, Human |
| Clone | REA1321 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | phycoerythrin (PE) conjugate |
| Size | 200 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD11b Antibody, anti-human, PE, REAfinity™. Clone REA1321 recognizes the human CD11b antigen (Mac-1 α; integrin αM chain), which is part of the CD11b/CD18 heterodimer (Mac-1 α, Mβ2 integrin), also known as the C3 complement receptor. It functions as a receptor for complement (C3bi), fibrinogen, or clotting factor X. In humans, CD11b is strongly expressed on myeloid cells. It is reported, that CD11b is able to control myeloid cell polarization and tumor growth. Furthermore, it induces cytotoxicity in ovarian cancer cells and is considered to be used as a therapeutic target. It is weakly expressed on natural killer (NK) cells and some activated lymphocytes as well as on microglia in the brain. Additional information: Clone REA1321 displays negligible binding to Fc receptors. | |
| Immunogen | n/a |
| Other Names | integrin αM, Mac-1 α, Integrin alpha-M, CR3A |
| Gene, Accession # | Gene ID: 3684 |
| Catalog # | 130-128-773 |
| Price | $285 |
| Order / More Info | CD11b, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | n/a |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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