CD161, human Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityCD161, human
CloneREA631
Host SpeciesRecombinant Human
Reactive Specieshuman
IsotypeIgG1
Formatallophycocyanin (APC) conjugate
Sizefor 30 tests
Concentration1:50
ApplicationsFlow cytometry
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DescriptionClone REA631 recognizes the human CD161 antigen, a 80 kDa single-pass type II membrane protein, which is also known as natural killer cell surface protein P1A (NKR-P1A) or C-type lectin domain family 5 member B (CLEC5B). CD161 is expressed on most natural killer (NK) cells and subsets of T cells. In peripheral blood, CD161 is preferentially expressed on T cells of memory phenotype, but it can also be found on subsets of thymocytes and fetal liver T cells. CD161 has been implicated in triggering NK-mediated cytotoxicity, contributing to target cell recognition by NK cells. | Additional information: Clone REA631 displays negligible binding to Fc receptors.
ImmunogenCD161
Other NamesNKR-P1A, HNKR-P1a, CLEC5B
Gene, Accession #Gene ID: 3820
Catalog #130-114-121
Price$128
Order / More InfoCD161, human Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesLanier, L. L. et al. (1994) Human NKR-P1A. A disulfide-linked homodimer of the C-type lectin superfamily expressed by a subset of NK and T lymphocytes. J. Immunol. 153: 2417-2428. | Pozo, D. et al. (2006) CD161 (human NKRP1A) signaling in NK cells involves the activation of acid sphingomyelinase. J. Immunol. 176: 2397-2406. | Takahashi, T. et al. (2006) Expression of CD161 (NKR-P1A) defines subsets of human CD4 and CD8 T cells with different functional activities.? J. Immunol. 176: 211-216.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

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