CD161, human Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityCD161, human
Clone191B8
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2aκ
Formatfluorescein (FITC) conjugate
Sizefor 30 tests
Concentration1:50
ApplicationsFlow cytometry
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DescriptionClone 191B8 recognizes CD161, a C-type lectin membrane glycoprotein. CD161, also known as NKR-P1A, is expressed as an 80 kDa disulfide-linked homodimer and is found on most NK cells and subsets of T cells. In peripheral blood, CD161 is preferentially expressed on T cells of memory phenotype, but it can also be found on subsets of thymocytes and fetal liver T cells. | CD161 has been implicated in triggering NK-mediated cytotoxicity, contributing to target cell recognition by NK cells.
ImmunogenCD161
Other NamesKLRB1, CLEC5B, NKR, NKR-P1, NKR-P1A, NKRP1A, HNKR-P1a
Gene, Accession #Gene ID: 3820
Catalog #130-114-118
Price$84
Order / More InfoCD161, human Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesLanier, L. L. et al. (1994) Human NKR-P1A. A disulfide-linked homodimer of the C-type lectin superfamily expressed by a subset of NK and T lymphocytes. J. Immunol. 153: 2417-2428. | Poggi, A. et al. (2002) Transendothelial migratory pathways of Vδ1+TCRγδ+ and Vδ2+TCRγδ+ T lymphocytes from healthy donors and multiple sclerosis patients: involvement of phosphatidylinositol 3 kinase and calcium calmodulin-dependent kinase II. J. Immunol. 168: 6071-6077. | Pozo, D. et al. (2006) CD161 (human NKRP1A) signaling in NK cells involves the activation of acid sphingomyelinase. J. Immunol. 176: 2397-2406. | Takahashi, T. et al. (2006) Expression of CD161 (NKR-P1A) defines subsets of human CD4 and CD8 T cells with different functional activities.? J. Immunol. 176: 211-216.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

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