ADAMTS13, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityADAMTS13, Human
CloneREA593
Host SpeciesRecombinant
Reactive Specieshuman
IsotypeIgG1
Formatphycoerythrin (PE) conjugate
Size30 tests in 300 µL
Concentration1:10
ApplicationsIntracellular flow cytometry
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionADAMTS13 Antibody, anti-human, PE, REAfinity™. Clone REA593 recognizes the human ADAMTS13 antigen, which is also known as von Willebrand factor-cleaving protease (VWFCP). ADAMTS13 is a disintegrin and metalloproteinase with a thrombospondin type 1 motif which splits the VWF multimers in plasma into smaller forms thereby controlling VWF-mediated platelet thrombus formation. ADAMTS13 is expressed in liver and secreted in blood. | Additional information: Clone REA593 displays negligible binding to Fc receptors. |
Immunogenn/a
Other NamesADAM-TS 13, vWF-CP, VWFCP
Gene, Accession #Gene ID: 11093
Catalog #130-109-315
Priceplease inquire
Order / More InfoADAMTS13, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesAkiyama, M. et al. (2009) Crystal structures of the noncatalytic domains of ADAMTS13 reveal multiple discontinuous exosites for von Willebrand factor. Proc. Natl. Acad. Sci. U.S.A. 106 (46): 19274-19279. | Soejima, K. et al. (2001) A novel human metalloprotease synthesized in the liver and secreted into the blood: possibly, the von Willebrand factor-cleaving protease? J. Biochem. 130 (4): 475-480. | Furlan, M. et al. (2001) Aetiology and pathogenesis of thrombotic thrombocytopenic purpura and haemolytic uraemic syndrome: the role of von Willebrand factor-cleaving protease. Best Pract Res Clin Haematol 14 (2): 437-454.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

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