CD182 (CXCR2), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityCD182 (CXCR2), Human
CloneREA208
Host SpeciesRecombinant Human
Reactive Specieshuman
IsotypeIgG1
Formatphycoerythrin (PE) conjugate
Size30 tests in 60 µL
Concentration1:50
ApplicationsFlow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
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DescriptionCD182 (CXCR2) Antibody, anti-human, PE, REAfinity™. Clone REA208 recognizes CD182 (CXCR2), which belongs to the class of chemokine receptors specific for CXC chemokines. Chemokine receptors are G-coupled protein receptors (GPCR) with seven-transmembrane domains and consist of an α-subunit and a βγ-complex. In humans, interleukin 8 (IL-8) is one of most potent chemokine which binds to CXCR2. Expression of CD182 is found on several cell types including leukocytes, endothelial, and epithelial cells. CD182 plays a critical role in neutrophil homeostatis, angiogenesis, and in pathological conditions such as acute lung injury, lung diseases, and asthma. | Additional information: Clone REA208 displays negligible binding to Fc receptors. |
Immunogenn/a
Other NamesCXCR2, CDw128b, CMKAR2, IL8R2, IL8RA, CD128b, IL-8RB
Gene, Accession #Gene ID: 3579
Catalog #130-126-197
Price$121
Order / More InfoCD182 (CXCR2), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesBelperio, J. A. et al. (2005) CXCR2/CXCR2 ligand biology during lung transplant ischemia-reperfusion injury. J Immunol 175: 6931-6939. | Thatcher, T. H. et al. (2005) Role of CXCR2 in cigarette smoke-induced lung inflammation. Am. J. Physiol. Lung Cell Mol. Physiol. 289: L322-L328.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

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