CD161, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD161, Human |
| Clone | 191B8 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2aκ |
| Format | PE-Vio® 770 conjugate |
| Size | 30 tests in 60 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD161 Antibody, anti-human, PE-Vio® 770. Clone 191B8 recognizes CD161, a C-type lectin membrane glycoprotein. CD161, also known as NKR-P1A, is expressed as an 80 kDa disulfide-linked homodimer and is found on most NK cells and subsets of T cells. In peripheral blood, CD161 is preferentially expressed on T cells of memory phenotype, but it can also be found on subsets of thymocytes and fetal liver T cells. | CD161 has been implicated in triggering NK-mediated cytotoxicity, contributing to target cell recognition by NK cells. |
| Immunogen | n/a |
| Other Names | KLRB1, CLEC5B, NKR, NKR-P1, NKR-P1A, NKRP1A, HNKR-P1a |
| Gene, Accession # | Gene ID: 3820 |
| Catalog # | 130-114-120 |
| Price | please inquire |
| Order / More Info | CD161, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Lanier, L. L. et al. (1994) Human NKR-P1A. A disulfide-linked homodimer of the C-type lectin superfamily expressed by a subset of NK and T lymphocytes. J. Immunol. 153: 2417-2428. | Poggi, A. et al. (2002) Transendothelial migratory pathways of Vδ1+TCRγδ+ and Vδ2+TCRγδ+ T lymphocytes from healthy donors and multiple sclerosis patients: involvement of phosphatidylinositol 3 kinase and calcium calmodulin-dependent kinase II. J. Immunol. 168: 6071-6077. | Pozo, D. et al. (2006) CD161 (human NKRP1A) signaling in NK cells involves the activation of acid sphingomyelinase. J. Immunol. 176: 2397-2406. | Takahashi, T. et al. (2006) Expression of CD161 (NKR-P1A) defines subsets of human CD4 and CD8 T cells with different functional activities.? J. Immunol. 176: 211-216. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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